l Lambar Cas: 171596-29-5 Molecular Formula: C₂₂H₁₉N₃O₄
| Matsayin narkewa | > 193 ° C |
| Yawan yawa | DMF: 25 mg/ml DMF: PBS (pH 7.2) (1:1): 0.5 mg/ml DMSO: 20 mg/ml |
| yanayin ajiya | -20°C |
| narkewa | DMF: 25 mg/ml DMF: PBS (pH 7.2) (1:1): 0.5 mg/ml DMSO: 20 mg/ml |
| aikin gani | [α]/D +68 zuwa +78°, c = 1 a cikin chloroform-d |
| Bayyanar | Fari zuwa Kashe-fari mai ƙarfi |
| Tsafta | ≥98% |
(sunan kasuwa ko) wani nau'i ne na PDE5 mai hanawa da ake amfani da shi don magance tabarbarewar mazakuta, hauhawar jini na prostatic da hauhawar jini na huhu.Sakamakon shine shakatawa tsokoki na jini da kuma ƙara yawan jini a cikin corpus cavernosum.Hanyar aikin shine ta hanyar hana ayyukan cGMP takamaiman nau'in phosphodiesterase 5 (PDE5).PDE5 yana rage darajar cGMP a cikin kogon corpus da ke kusa da azzakari.Sabili da haka, tadalafi yana haifar da haɓakar haɓakar cGMP wanda ya kara haifar da sassaucin ƙwayar tsoka da kuma ƙara yawan jini a cikin corpus cavernosum.Wasu nazarin asibiti kuma sun nuna cewa zai iya inganta aikin endothelia a cikin maza tare da ƙara haɗarin zuciya da jijiyoyin jini da rage alamun urinary fili na biyu zuwa hyperplasia na prostate.
analgesic, mai karewa, mu-opiod receptor agonist.A phosphodiesterase 5 inhibitor.ana amfani da shi don maganin tabar wiwi.
ya bambanta da tsari daga duka sildenafil da vardenafil.Ana ɗaukar shi da sauri kuma yana haɓaka cikin maida hankali (378 μg / L bayan kashi na 20-MG) bayan sa'o'i 2, yana nuna tsawon rabin rayuwar sa'o'i 17.5.Hakanan yana haɓaka ta hanta (CYP3A4).Musamman ma, magungunan sa ba sa tasiri a asibiti ta hanyar barasa ko ci abinci ko ta dalilai kamar su ciwon sukari ko nakasa aikin hanta ko na koda.
