Lambar Cas: 21187-98-4 Tsarin Halitta
Matsayin narkewa | 163-169 ° C |
Yawan yawa | 1.2205 (ƙananan ƙididdiga) |
yanayin ajiya | Yanayin rashin aiki, Zazzabin ɗaki 2-8°C |
narkewa | Methylene chloride: mai narkewa |
aikin gani | N/A |
Bayyanar | Kashe-White Solid |
Tsafta | ≥98% |
wakili ne na baka na antihyperglycemic da ake amfani dashi don maganin ciwon sukari mellitus nau'in II.Yana cikin rukunin sulfonylurea na asirin insulin, wanda ke motsa sel β na pancreas don sakin insulin.yana ɗaure da β cell sulfonyl urea receptor (SUR1), yana ƙara toshe tashoshin potassium masu mahimmanci na ATP.Sabili da haka, ƙwayar potassium yana raguwa sosai, yana haifar da lalata ƙwayoyin β.Sannan tashoshin calcium masu dogaro da wutar lantarki a cikin tantanin halitta na β suna buɗe, wanda ke haifar da kunnawa calmodulin, wanda hakan ke haifar da exocytosis na insulin mai ɗauke da granules na sirri.Binciken da aka yi kwanan nan ya nuna cewa zai iya inganta yanayin anti-oxidant da nitric oxide-mediated vasodilation a cikin nau'in ciwon sukari na 2 da kuma kare kwayoyin beta-pancreatic daga lalacewa ta hanyar hydrogen peroxide.
maganin ciwon sukari ne na baka da ake amfani da shi don magance ciwon sukari wanda ba ya dogara da insulin. abinci zuwa makamashi.yana rage matakan glucose na jini ta hanyar haɓaka fitar da insulin daga ƙwayoyin β-sel na tsibiran Langerhans.