Rifampicin Cas lambar: 13292-46-1 Tsarin kwayoyin halitta: C43H58N4O12
| Matsayin narkewa | 183 ° |
| Yawan yawa | 1.1782 |
| yanayin ajiya | 2-8 ° C |
| narkewa | chloroform: mai soluble 50mg/ml, bayyananne |
| aikin gani | N/A |
| Bayyanar | ja mai laushi zuwa ja mai duhu sosai |
| Tsafta | ≥99% |
Rifampicin wani nau'in sinadari ne na rifamicin B, maganin rigakafi na macrolactam da kuma ɗayan maganin rigakafi sama da biyar daga cakuda rifamicin A, B, C, D, da E, wanda ake kira rukunin rifamicin, wanda actinomycetes Streptomyces mediteranei ke samarwa ( Nocardia mediteranei).An gabatar da shi a cikin aikin likita a cikin 1968. Haɗin rifampicin yana farawa da maganin ruwa mai ruwa na rifamicin, wanda a ƙarƙashin yanayin halayen yana oxidized zuwa sabon abin da aka samu na rifamicin S (32.7.4), tare da samuwar tsaka-tsakin rifamicin O (32.7. 3).Rage tsarin quinone na wannan samfur tare da hydrogen ta amfani da palladium akan mai kara kuzari yana ba da rifamicin SV (32.7.5).Samfurin da aka samu yana jurewa aminomethylation ta hanyar cakuda formaldehyde da pyrrolidine, yana ba da 3-pyrrolidinomethylrifamicin SV (32.7.6).Oxidizing da sakamakon samfurin tare da gubar tetracetate zuwa enamine da na gaba hydrolysis tare da ruwa bayani na ascorbic acid yana ba da 3-formylrifamicin SV (32.7.7).Amsa wannan tare da 1-amino-4-methylpiperazine yana ba da rifampicin da ake so (32.7.8).
Ana amfani da Rifampin azaman maganin rigakafi.Siffar sinadari ce ta rifamycin B, maganin rigakafi na macrocyclic wanda mold Streptomyces mediterranei ya samar.Ana amfani da Rifampin don maganin tarin fuka, brucellosis, Staphlococcus aureus, da sauran cututtuka masu yaduwa.
