Lambar Cas: 224785-91-5 Molecular Formula: C23H33ClN6O4S

Takaitaccen Bayani:

Lambar Cas: 224785-91-5

Sunan Sinadari:

Tsarin kwayoyin halitta:Saukewa: C23H33ClN6O4S

Synonyms: HCL;Vardenafi;Nuviva;fafinafei;Valdenafil;Levitra,Valdenafil;USP/EP/BP;Levitra,Valdenafil.HCl;224785-91-5;

Aika mana imel

Cikakken Bayani

Tags samfurin

Ƙayyadaddun samfuran

Matsayin narkewa	214-216 ° C
Yawan yawa	N/A
yanayin ajiya	Yanayin rashin aiki, 2-8°C
narkewa	N/A
aikin gani	N/A
Bayyanar	Fari zuwa Kashe-Farin Cyrstalline
Tsafta	≥98%

pharmacodynamics

shi ne wakili na biyu da za a tallata kuma yana da fa'ida cewa ba a rage lokacin farawa ta hanyar shan magani a cikin cikakken ciki ba.Yana da sau 30 mafi ƙarfi a matsayin mai hanawa na PDE5 (ma'anar IC50, 3.9 nM) fiye da sildenafil da 10 sau da yawa fiye da tadalafil, tare da zaɓi mafi girma (> 1,000 sau) don PDE5 na ɗan adam fiye da PDE2, PDE3, da PDE4 da matsakaicin zaɓi (> sau 80) don PDE1.Zaɓin inhibitory PDE da duka in vitro da in vivo ƙarfin sabon mai hana PDE5.musamman hana hydrolysis na cGMP ta PDE5, tare da IC50 na 0.7 nM (sildenafil 6.6 nM).IC50 na PDE1 shine 180 nM, don PDE6 11 nM, kuma don PDE2, PDE3 da PDE4 fiye da 1,000 nM.